What Could
Go Right?
The Podcast

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The Case for Not Knowing

Featuring Simone Stolzoff

What happens when our biological need for certainty clashes with an increasingly unpredictable world? Simone Stolzoff, author of How to Not Know, joins host Zachary Karabell to discuss why our modern intolerance for uncertainty is fueling a global anxiety crisis. Rather than seeing the unknown as a threat, Stolzoff argues that uncertainty is the fundamental birthplace of scientific breakthroughs, original art, and human progress.

Gene Therapy Is Giving Blind People Their Sight Back

Featuring Emma Varvaloucas

Gene therapy has been quietly pulling off miracles, and this week, it got its Oscars moment. Emma Varvaloucas, Executive Director of The Progress Network, breaks down how a husband-and-wife scientific team's decades-long quest has restored sight to over 100 blind Americans, and how a brand-new drug called Otarmeni just became the first-ever FDA-approved gene therapy for genetic deafness. The science is extraordinary. The price tags, less so.

Why $6 Gas Isn’t the End of the World

Featuring Jason Bordoff

What happens when the global energy supply faces its greatest disruption since the 1970s? Jason Bordoff, a leading energy expert and former advisor in the Obama White House, joins host Zachary Karabell to navigate a world where the Strait of Hormuz is closed and gasoline prices are soaring.

ALL EPISODES

Featuring Simone Stolzoff

The Case for Not Knowing

What happens when our biological need for certainty clashes with an increasingly unpredictable world? Simone Stolzoff, author of How to Not Know, joins host Zachary Karabell to discuss why our modern intolerance for uncertainty is fueling a global anxiety crisis. Rather than seeing the unknown as a threat, Stolzoff argues that uncertainty is the fundamental birthplace of scientific breakthroughs, original art, and human progress.

Featuring Emma Varvaloucas

Gene Therapy Is Giving Blind People Their Sight Back

Gene therapy has been quietly pulling off miracles, and this week, it got its Oscars moment. Emma Varvaloucas, Executive Director of The Progress Network, breaks down how a husband-and-wife scientific team's decades-long quest has restored sight to over 100 blind Americans, and how a brand-new drug called Otarmeni just became the first-ever FDA-approved gene therapy for genetic deafness. The science is extraordinary. The price tags, less so.

Featuring Jason Bordoff

Why $6 Gas Isn’t the End of the World

What happens when the global energy supply faces its greatest disruption since the 1970s? Jason Bordoff, a leading energy expert and former advisor in the Obama White House, joins host Zachary Karabell to navigate a world where the Strait of Hormuz is closed and gasoline prices are soaring.

MEET OUR
HOSTS

Zachary Karabell

Zachary Karabell is the founder of the Progress Network. He is an author, columnist, and investor and president of River Twice Capital. He is also the author of 13 books, most recently Inside Money: Brown Brothers Harriman and the American Way of Power.

Zachary Karabell

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Emma Varvaloucas

Emma Varvaloucas is the Executive Director of The Progress Network. An editor and writer specializing in nonprofit media, she was formerly Executive Editor of Tricycle: The Buddhist Review and is the editor of two books from Wisdom Publications.

Emma Varvaloucas

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Testimonials

This podcast is optimistic without being naive. Deeply historically based reflections met with global comparisons on the troubling issues we face today. Excited for the next conversation!

Katelyn

Love this fresh perspective—a welcome listen during these transitional times.

Lara

What Could Go Right? is one of the best projects on the Internet. Chin up, people—believe it or not, we're somehow moving in the right direction in many ways.

Chris

Your podcast with Anne-Marie Slaughter was fabulous. . . . More things like this and thank you for your platform of caring, brilliant leaders. We need your perspective to heal!

Cheryl